Tool Developed for Study of Stem Cell Transplants May Treat HIV


Dr Jonah Sacha and colleagues from OHSU Vaccine And Gene Therapy Institute have developed a new way to understand what cured the patient in Berlin after he was given a stem cell transplant for the treatment of cancer, which in turn cleared him of HIV! Dr Sacha and his team have proven that the species of monkeys called Mauritian cynomolgus macaques can successfully receive stem cell transplants. This is a huge step because from very long, researchers have been experimenting with different species of monkeys for their research on stem cell transplant but biological characteristics of all these species proved to be unreliable for finding a good match that can mimic human stem transplants.

Stem Cell Transplants Experiment on Mauritian Cynomolgus Macaques Species of Monkeys Turned Out Successful

 The recently published paper by Sacha and his colleagues have reported that they successfully performed stem cell transplants on two monkeys of the Mauritian cynomolgus macaques species a year ago and that these two monkeys are living a healthy life today without suffering from any side effects from stem transplant, severe liver damage, diarrhea, rashes, or even death. These findings are also providing Sacha and his colleagues with an important tool that is required to explore and solve the mystery of how the Berlin patient was cured. As a result of the successful experiment on this species of monkeys, further studies can now be done to improve the outcome of stem cell transplant for treating humans with blood related conditions such as leukemia.

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