In the last research study that was published in this year earlier in the Nature Medicine that involved University of Minnesota Medical School faculty Laura J. Niedernhofer and Paul D. Robbins and the investigators from the Mayo Clinic Tamara Tchkonia and Janes L. Kirland have stated that it is possible now to lessen the burden of the damaged cells that have been termed as senescent cells and further improve the health and extend the lifespan. This can be made possible even when the treatment was initiated in the life.
Furthermore, they have showcased the treatment of aged mice the natural product Fisetin, which is found in several vegetables and fruits and also offers positive effects on the lifespan and health. As the age increases, the body accumulates damaged cells. After the cells get to a specific level of damage then they go through a complete aging process of their own, which is known as cellular senescence. These cells later release inflammatory factors that inform the immune system to clear the damaged cells. The immune system of a younger person is comparatively quite healthy and it helps in clearing the damaged cells. On the other hand, when the age of a person increases, the damaged cells do not get cleared effectively. As a result, they start getting accumulated, which further causes a low level inflammation and then releases enzymes degrading the tissue.
The team of researchers have discovered a natural product, which has been named as Fisetin that reduces the level of the damaged cells in the body. An experiment was recently conducted by treating the mice at the end of the life making use of this compound and have recorded the improvements in the lifespan and health.