Mesh implants used in numerous surgical interventions always bear the risk of a range of complications such as chronic fatigue, cognitive impairment, muscle and joint pain, and dry mouth. They are frequently used in hernia repair and urogynecologic procedures. Of all these complications, symptoms of autoimmune disorders in the patients have surfaced as the most crucial. A recent study by a researcher from University of Alberta, Canada taking a closer look at the association has found that the symptoms are not merely coincidences. Rather, he strongly believes that the usage of surgical mesh implants may be the key determinant in causing autoimmune disorders in patients. The researcher has revealed the results at 11th International Conference on Autoimmunity in Lisbon in May 2018 and hopes to publish the findings soon in some leading journal.
People with Genetic Triggers found to be Most Vulnerable to Risks
The rheumatologist in his study found that as many as 40 patients had suffered with the common risks after undergoing surgical interventions with mesh implants. Unsurprisingly, almost 45% of these developed autoimmune-triggered inflammatory diseases, notably lupus and rheumatoid arthritis. On top of that, patients who already had allergic risks suffered most. The study found that not all people are at potential risks, but only those that have genetic triggers or basis. However, this doesn’t mean that patients with pre-existing allergies should panic but only that they need to be discuss the concomitant risks with the caregivers including their plastic surgeons.
The researchers has suggested a way out of this. He proposes an effective genetic test in people who need surgical mesh implants to know the extent of vulnerability.
Larger Trials Needed to Confirm Findings
Several large-scale studies have established that people with breast implants display autoimmune/autoinflammatory syndrome induced by adjuvants (ASIA) and indeed are potentially at higher risk of autoimmune disorders. In fact, the symptoms faded or got completely cured when the implants were removed, stated the researcher.
The implications of the study, though small in sample size, are crucial for surgeons and patients with mesh implants. Larger and more randomized studies are needed for arriving at any definitive result, the researcher concluded.