In a recent study that analyzed 107 brains of aged human beings, researchers have found out certain details that would further help in the understanding of biological bases for diseases that are related to old age like dementia and Alzheimer’s. Dementia and Alzheimer’s affect a large chunk of the aging population across the globe.
New Study Examines the Relation between Dementia and RNA
The study was carried out by researchers at Allen Institute for Brain Science, Kaiser Permanente Washington Health Research Institute and University of Washington School of Medicine. The study brings forth surprising variability that is found in aged brains and that includes instances of donors who have developed resilience towards pathology.
Ed Lein, a researcher at Allen Institute for Brain Science emphasizes the importance of such a research citing the increasing population of people over 90 years of age. He says that there is a need for understanding both age-related disease and healthy aging.
The findings of the research revealed that people who are aged more than 85 years showed correlation between plaques and tangles that are associated with Alzheimer’s and decline of cognitive abilities.
Dr. Jeremy Miller, Senior Scientist, Allen Institute for Brain Science emphasized on the importance of quality of the genetic material in the study of diseases. The findings of the study underline the necessity of proper controlling of Ribonucleic acid (RNA) while researching on the aged brain. He hinted that degradation in the quality of genetic material could be the underlying cause for dementia.
The findings of the research has been published in the journal titled eLife and the data from the research is available for the public.