Around two-thirds of the U.S. denture-wearing population is affected with frequent fungal infections that result in swelling, redness, and inflammation in the mouth.
To improve treatment of these infections, called denture-related stomatitis, researchers at University of Buffalo have turned to 3-D printers, making use of the machines so as to build dentures that is filled with microscopic capsules which periodically release Amphotericin B, an antifungal medication.
Drug-filled Dentures can Diminish Fungal Growth
A research describing the work has discovered that the drug-filled dentures can diminish fungal growth. Unlike current options of treatment, such as microwave disinfection, baking soda, and antiseptic mouthwashes, the new development can also assist in the prevention of infection whilst the dentures are in use.
Praveen Arany, DDS, PhD, the study’s senior author and an assistant professor in the Department of Oral Biology in the UB School of Dental Medicine said that the significant impact of this innovative 3-D printing system is its potential to impact on saving time and cost.
The technology enables clinicians to rapidly generate customized dentures chair-side, an immense improvement over conventional manufacturing that varies from a few days to weeks, says Arany. Praveen Arany also has an appointment in UB’s Department of Biomedical Engineering, a joint program in the Biomedical Sciences at UB and the School of Engineering and Applied Sciences and Jacobs School of Medicine.
Arany also says that applications from this research could be applied to many other clinical therapies comprising prosthesis, casts, stents, and splints.
The research has recently been published on Materials Today Communications.