Injury from shrapnel is a penetrating one and is a serious obstacle in overcoming wounds sustained in the battlefield can eventually result in death. Given the high rate of mortality owing to hemorrhaging, there exists an unmet requirement to rapidly self-administer materials so as to prevent fatality owing to excessive loss of blood.
A gelling agent is mostly utilized in the preparation of pastries, scientists from the Inspired Nanomaterials and Tissue Engineering Laboratory have successfully come up with an injectable bandage so as to stop bleeding and thereby promoting healing of wound.
Injectable Hydrogels Offers Hope for Hemostasis
In a recent article bearing the title “Nanoengineered Injectable Hydrogels for Wound Healing Application”, Dr. Akhilesh K. Gaharwar, assistant professor in the Department of Biomedical Engineering at Texas A&M University, has said that he has used nanosilicates and kappa-carrageenan so as to form injectable hydrogels and promote hemostasis which is the process to stop bleeding and facilitate healing of wound healing through controlled release of therapeutics.
He further said that injectable hydrogels are considered as promising materials for the purpose of achievement of hemostasis in case of bleeding and internal injuries, as these biomaterials can be applied to a wound site by making use of approaches which are minimally invasive. The most appropriate injectable bandage should become a solid after injection in the area of the wound and promote a natural cascade of clotting. In addition to that, the injectable bandage should also start healing response of wound after achieving hemostasis.
The research makes use of an extensively used thickening agent called as kappa-carrageenan which is obtained from seaweed, to make injectable hydrogels. Hydrogels refers to a 3-D water swollen polymer network which is similar to Jell-O thereby simulating human tissue structure.
The article has been published on Acta Biomaterialia.