Genetic Risk of Heart Disease is Reduced by Increased Physical Activity

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Even when one is born with high genetic risk for heart disease, keeping fit still works to keep one’s heart healthy; this is the latest findings in accordance to a study that is led by researchers at the Stanford University School of Medicine.

In one of the largest observational studies on heart disease and fitness, researchers made an examination of data that has been collected from nearly half-million people in the database of UK Bio-bank. They discovered that people with higher levels of cardio-respiratory fitness, physical activity, and grip strength had reduced risks of stroke and heart attacks, even if they come with a genetic predisposition for heart disease.

Study Findings to Have Significant Ramifications on Public Health

Erik Ingelsson, MD, PhD, professor of cardiovascular medicine, said that people should not give up exercising as they come with a high genetic risk for heart disease and even if one does not have such high genetic risk, nevertheless, one should not stop exercising. It has been a combination of environment and genes that influence health.

The lead author of this research is Dr. Emmi Tikkanen, PhD, a former postdoctoral scholar at Stanford University and he is now senior data scientist at Nightingale Health Ltd. in Finland.

Given whatever little is known about the risk-modifying effects of exercise in many of the individuals who come with increased genetic risk of cardiovascular disease, these findings could have important ramifications on the public health, as the said study concludes.

Researchers have discovered across the board that higher levels of physical and fitness activities are associated with lower levels of numerous negative cardiovascular outcomes, comprising atrial fibrillation, stroke, and coronary artery disease.

The said research paper will be published online on Circulation, a scientific journal, with Ingelsson as a senior author.

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