Early detection of cancer can help doctors save patients’ lives with less risks. Detection of ovarian cancer is difficult as symptoms usually surface at the later stage. Thus, researchers are looking to manufacture latest tools to detect cancer easily at an early stage.
Researchers from the University of Kansas (KU) in Lawrence developed sensitive cancer-detecting devices. The researchers did this working with the KU Cancer Center and KU Medical Center in Kansas City.
The device called “3-D-nanopatterned microfluidic chip” is able to detect cancer successfully by testing tiniest drop of blood.
Yong Zeng, the lead author of the study, said the device identifies and diagnoses cancer by filtering exosomes. They contain biological information, which can explain tumor growth. Exosomes are often called trash bags or the cells for dumping unwanted cellular content. However, from the past few years researchers are considering them as useful recipient cells for communicating molecular information in biological functions.
A highly sensitive diagnostic device
The device is a 3D nanoengineering tool using a herringbone pattern, which examines exosomes. Researchers manufactured the device by eliminating the requirement of complex features of structures with 3-D nanoporous herringbone. Additionally, the device can drain liquid to bring the particles in contact with the surface.
Scientists tested the chips on ovarian cancer cells. During the tests, the chip successfully detected cancer with the tiniest amount of blood and plasma.